Neurodegenerativedisease相关论文
Diagnosing Alzheimer\'s disease(AD)in the early stage is challenging.Informative biomarkers can be of great value for ......
miRNA are short non-coding RNA responsible for the knockdown of proteins through their targeting and silencing of compli......
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3-Nitropropionic acid modifies neurotrophin mRNA expression in the mouse striatum:18S-rRNA is a reli
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A plethora of evidence suggests that protein misfolding and aggregation are underlying mechanisms of various neurodegene......
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Regeneration of functional neurons in neurodegenerative diseases or after brain injury holds great promise for future th......
Emerging evidence has implicated dysfunctional autophagy in a growing number of neurodegenerative diseases,including Par......
Study Objectives: To determine the mortality and its risk factors in patients with rapid eye movement(REM)sleep behavior......
Xanthoceraside improves memory and reduces hyperphosphorylated tau in intracerebroventricular-strept
Alzheimers disease is a progressive neurodegenerative disease characterized by amyloid plaques, neurofibrillary tangles ......
Study Objectives: To determine the association of excessive daytime sleepiness(EDS)with the conversion of neurodegenerat......
Neuroprotective effects of Amerlcan ginseng extract on neurodegenerative dlsease In rats: Neurochemi
American ginseng extract (AGE) has been shown to have a lot of beneficial effects on disorders of central nervous system......
Over twenty diseases are associated with amyloid deposits,such as Alzheimers disease,Parkinson′s disease and Huntington......
Maintaining proteostasis is an essential housekeeping function for cell survival.It involves chaperones and degradative ......
Design of functional small interfering RNAs targeting amyotrophic lateral sclerosis-associated mutan
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Relationships between Rapid Eye Movement Sleep Behavior Disorder and Neurodegenerative Diseases: Cli
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神经退行性疾病是一类严重危害人类健康的中枢神经系统变性疾病。补体3(C3)-补体3a受体(C3aR)通路是经典补体激活的重要通路之一。......
The cyclin-dependent kinase 5(CDK5)activators,p35 and p25,have a proposed role in the pathogenesis of neurodegenerat......
TAR DNA/RNA结合蛋白43 (TARDNA/RNA-binding domain protein 43,TDP-43)是一种高度保守、广泛表达的核蛋白.肌萎缩侧索硬化症(amy......
双重任务行走(dual task walking，DTW)是指在自然行走的同时执行另一项注意力需求的任务。在日常生活中很常见，如行走时的交谈，或者穿......
Effects of MCI-186 on intracellular calcium ion concentration and membrane fluidity of hippocampal n
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Metabolic alteration of neuroactive steroids and protective effect of progesterone in Alzheimer’s di
A correlation between metabolic alterations of neuroactive steroids and Alzheimer’s disease remains unknown. In the pre......
Neuroacanthocytosis is an autosomal recessive or dominant inherited disease characterized by widespread, non-specific ne......
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Nasal mucosal inhalation of amyloid-beta peptide 3-10 defective adenovirus attenuates cytotoxicity i
Three-month-old Alzheimer’s disease model transgenic mice were immunized with Aβ1-42, Plp-Adenovirus [Ad]-X-CMV-(Aβ3-......
Our previous studies have revealed that amyloid β(Aβ)-binding alcohol dehydrogenase(ABAD) decoy peptide antagonizes A......
Construction of a plasmid for human brain-derived neurotrophic factor and its effect on retinal pigm
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Effects of triptolide on hippocampal microglial cells and astrocytes in the APP/PS1 double transgeni
The principal pathology of Alzheimer’s disease includes neuronal extracellular deposition of amyloid-beta peptides and ......
BACE1 in the retina：a sensitive biomarker for monitoring early pathological changes in Alzheimer’s d
Because of a lack of sensitive biomarkers, the diagnosis of Alzheimer’s disease (AD) cannot be made prior to symptom ma......
Mesenchymal stem cell-derived exosomes promote neurogenesis and cognitive function recovery in a mou
Graphical Abstract Abstract Studies have shown that mesenchymal stem cell-derived exosomes can enhance neural plasticity......
Characteristics and advantages of adeno-associated virus vector-mediated gene therapy for neurodegen
Common neurodegenerative diseases of the central nervous system are characterized by progressive damage to the function ......
Oxygen is essential to the human life and life of all aerobic organisms.The complete oxidation of nutrients for the biol......
线粒体自噬(mitophagy)是指细胞通过自噬的机制选择性地清除线粒体的过程,对于整个线粒体网络的功能完整性十分关键,决定细胞的生......
自噬是通过对衰老蛋白、受损细胞器消化降解再利用来维持细胞正常稳态的一个动态的过程。近年来随着学者对自噬研究的深入，发现自噬......
In order to explore the role of TNF-a in Niemann-Pick type C (NPC) disease,lentivi-ral-delivered RNA interference (RNAi)......
目的：探讨老年帕金森病患者发生认知障碍的影响因素。方法将74例老年帕金森病患者按有无认知障碍分为观察组31例和对照组43例，统计两......
BACKGROUND: Neural regeneration fol owing nerve injury is an emerging field that attracts ex-tending interests al over t......
